Stem Cells Therapy for Liver Cirrhosis

Chronic liver failure is known to be the fifth biggest killer in developed countries. Although the liver is known to be the organ with the enhanced power of regeneration, significant damage to it may lead to its permanent loss of ability; which can lead to a life-threatening problem. Currently, a liver transplant is the only full-proof treatment; which could alter the condition. Although, in today’s scenario due to increased disease-specific socioeconomic burden, even the demand for organs is so high that patients have to wait for their entire life in search of suitable organs.

The liver has been offered very much importance in performing different tasks such as removing blood toxins, digesting food, and fighting against infection and is known to be the biggest reservoir of blood in the body. These are some of the specific reasons, why liver problems should be considered a major health issue and not just a disease. There are over 100 different reasons, which can risk our liver; such as alcohol consumption, obesity, genetic problems, autoimmune disorders, etc.

Liver, like other important functional organs of the body; is made up of many different cells, from which hepatocytes are the leading players. On average, each hepatocyte comes up with a life expectancy of 300 days. These liver cells can make generous copies of themselves to make up the routine damage associated with the condition. However, in the case of severely progressive liver injury, the damage is so high that there is an increased demand for an external supply of stem cells, which can intuitively regenerate cells and restore their function back.

Research has advanced and many facets of stem cells are explored to gain a better understanding of how new stem cell-based therapies could work. It has been observed that once pushed inside the body after isolation and induced laboratory enrichment, these cells can migrate at the site of injury due to their strong signaling sense. They can regulate the body’s immune system to subside the initial signs of inflammation and can initiate regeneration of lost or weakened cells to boost the overall working capacity of the organ.

As such stem cell treatments still need to undergo a lot of development but those who are just on the verge of losing it due to their liver problems can try this option; which can definitely stop the progressive damage if not alter the condition.